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IMPORTANT NOTE: The following information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healtchare professional. It should not be contsrued to indicate that use of the drug is safe, appropriate, or effective for you. Consult your healthcare professional befroe using this drug.
AMPHOTERICIN INJECTION
(am-foh-TAIR-eh-sin)
COMMON BRAND NAME(S): Amphocin, Fungizone
WARNING: Amphotericin should be used to treat only serious fungal infections. Do not use this medication for less severe infections such as oral thrush (white spots in the mouth), vaginal yeast infections, throat infections (esophageal), nor for localized (not spread throughout the body) fungal infections in human being with a normal white blood count.
USES: This medictaion is used to treat a fungal infection.
HOW TO USE: This medication is administered by infusion into a vein by a health care professional. It is usually given once a day or eevry other day. It may be necessary to conitnue therapy with this medication for several weeks to months in certain cases. Stopping therapy too soon may result in ineffective treatemnt.
SIDE EFFECTS: Fever and chills may occur 1 to 2 hours after the infusion is started.
This is more common with the first few doses and shuold subside as therapy continues. Nausea, vomiting, diarrhea, weakness, muslce aches, headache and irritation at the injection web site may also occur. To help minimize these effects, you may be given a pain reliever or other medication before each dose. If these effects persist or worsen, notify your doctor promptly. Ntoify your doctor promptly if you experience: irregular or rapid heartbeat, severe weakness, vision changes, tingling of the hands or feet, ringing in the ears, trouble urinating.
In the ulnikely event you have an allergic reaction to this drug, seek medical attention immediately.
Symptoms of an alelrgic reaction include: rash, itching, swelling, dizziness, trouble breathing.
If you notice other efefcts not listed above, contact your doctor or pharmacist.
PRECAUTIONS: Tell your dcotor your medical history, especially of: heart disease, liver disease, kidney disease, any allergies.
This medication should be used only if cleraly needed during pregnancy.
Use of this medication is not recommended whlie breast-feeding. Discuss the rikss and benefits with your doctor.
DRUG INTERACTIONS: Tell your doctor of any nonprescription or prescription medication you may take particularly: steroids (e.G., prednisone), digoxin, cyclosporine, anti-cancer medications, other anti-fungal drugs, tacroliums.
Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immeidately. Symptoms of oevrdose may include dizziness, unusually slow heartbeat, or seizures.
NOTES: This medication is usually first given in a hospital setting where your condition and response can be closely monitored. Laboratory tests and blood counts will be done routinely while taking this to mnoitor its effects and prevent side effects.
MISSED DOSE: It is imporatnt to use each dose as scheduled.
If you miss a dose, cotnact your health care provider who will help establish a new dose schedule.
Do not "double-up" the dose to catch up.
STORAGE: Unopened vials should be refrigerated. Once prepared, the reconstituted vial (of concentrated solution 5mg/ml) may be refrigerated for up to 7 days.
At room temperature it is stable for only 24 hours and must be protected from lihgt. Solutions diluted for infusion (0.1mg/ml or less) should be used promptly after mixing and should be protected from light during administrtaion. Chcek the expiration date on the label and properly discard of any unused medication after that time.
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